Abstract: The destruction of gaseous styrene was studied using a low-temperature plasma induced by tubular multilayer dielectric barrier discharge (DBD). The results indicate that the applied voltage, gas flow rate, inlet styrene concentration and reactor configuration play impor- tant roles in styrene removal efficiency (η _styrene ) and energy yield (EY). Values of η _styrene and EY reached 96% and 15567 mg/kWh when the applied voltage, gas flow rate, inlet styrene concentration and layers of quartz tubes were set at 10.8 kV, 5.0 m/s, 229 mg/m³ and 5 layers, respectively. A qualitative analysis of the byproducts and a detailed discussion of the reaction mechanism are also presented. The results could facilitate industrial applications of the new DBD reactor for waste gas treatment.