Plasma-activated hydrogel: fabrication, functionalization, and effective biological model

Jiacheng LI; Cuntao LAN; Lanlan NIE; Dawei LIU; Xinpei LU

doi:10.1088/2058-6272/accb24

Plasma Science and Technology > 2023 > 25(9): 093001. > DOI: 10.1088/2058-6272/accb24

Jiacheng LI, Cuntao LAN, Lanlan NIE, Dawei LIU, Xinpei LU. Plasma-activated hydrogel: fabrication, functionalization, and effective biological model[J]. Plasma Science and Technology, 2023, 25(9): 093001. DOI: 10.1088/2058-6272/accb24

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Plasma-activated hydrogel: fabrication, functionalization, and effective biological model

1.
State Key Laboratory of Advanced Electromagnetic Engineering and Technology, School of Electrical and Electronic Engineering, Huazhong University of Science and Technology, Wuhan 430074, People's Republic of China
2.
Wuhan National High Magnetic Field Center, Wuhan 430074, People's Republic of China

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Corresponding author:
Dawei LIU, E-mail: liudw@hust.edu.cn

Xinpei LU, E-mail: luxinpei@hotmail.com
Received Date: December 04, 2022
Revised Date: March 31, 2023
Accepted Date: April 05, 2023
Available Online: December 05, 2023
Published Date: May 18, 2023

Graphical Abstract

Abstract

Abstract

Hydrogels are biomaterials with 3D networks of hydrophilic polymers. The generation of hydrogels is turning to the development of hydrogels with the help of enabling technologies. Plasma can tailor the hydrogels' properties through simultaneous physical and chemical actions, resulting in an emerging technology of plasma-activated hydrogels (PAH). PAH can be divided into functional PAH and biological tissue model PAH. This review systematically introduces the plasma sources, plasma etching polymer surface, and plasma cross-linking involved in the fabrication of PAH. The 'diffusion-drift-reaction model' is used to study the microscopic physicochemical interaction between plasma and biological tissue PAH models. Finally, the main achievements of PAH, including wound treatment, sterilization, 3D tumor model, etc, and their development trends are discussed.
- plasma-activated hydrogel,
- plasma crosslinking,
- biological model

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Acknowledgments

This work was supported by National Natural Science Foundation of China (No. 52277149) and the Inter-disciplinary Program of Wuhan National High Magnetic Field Center (No. WHMFC202144), Huazhong University of Science and Technology.

References (68)

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Plasma-activated hydrogel: fabrication, functionalization, and effective biological model

Abstract